NaturalFatBurn

Hoodia gordonii, "Whoo De AH", is the botanical name for a leafless, spiky succulent plant that grows throughout the semi-arid areas of Southern Africa primarily the Kalahari desert. The San (local inhabitants) have rationally used Hoodia stems to stave off hunger and thirst when on long journeys, as it acts as an appetite suppressant.

The use of Hoodia spp. has long been known by the indigenous populations of Southern Africa, who infrequently use these plants for treating indigestion plus small infections. However, it's their centuries old use of the meat of the plant to suppress appetite when making long hunting trips in the Kalahari Desert that has stimulated the most interest.

In 1977, the South African Council for Scientific plus Industrial Research (CSIR) isolated the ingredient in hoodia—now known as P57—which is responsible for its appetite-suppressant effect, plus patented it in 1996. The CSIR then granted United Kingdom-based Phytopharm a license, plus they collaborated with the pharmaceutical company Pfizer to isolate active ingredients from the extracts plus look into synthesizing them for use as an appetite suppressant. Pfizer released the rights to the primary ingredient in 2002. Paul Hutson, associate professor in the University of Wisconsin-Madison School of Pharmacy, told the Wisconsin State Journal, "For Pfizer to release something dealing with obesity suggests to me that they felt there was no merit to its oral use".Pfizer states that development on P57, the active ingredient of hoodia, was stopped due to the difficulty of synthesizing P57.Jasjit Bindra, lead researcher for hoodia at Pfizer, states there were indications of unwanted effects on the liver caused by other components, which could not be easily removed from the supplement, adding "Clearly, hoodia has a long way to go before it can earn approval from the Food plus Drug Administration (FDA). Until safer formulations are developed, dieters should be wary of using it."

In 2002, CSIR officially recognized the San tribespeople’s rights over hoodia, allowing them to take a percentage of the profits plus any spin-offs resulting from the marketing of hoodia. Hoodia gordonii is a protected plant which may only be wild-harvested by individuals plus the few companies who have been granted a license.


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